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Ice-recrystallization inhibiting polymers protect proteins against freeze-stress and enable glycerol-free cryostorage

Proteins are ubiquitous in molecular biotechnology, biotechnology and as therapeutics, but there are significant challenges in their storage and distribution, with freezing often required. This is traditionally achieved by the addition of cryoprotective agents such as glycerol (or trehalose) or cova...

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Detalles Bibliográficos
Autores principales: Mitchell, Daniel E., Fayter, Alice E. R., Deller, Robert C., Hasan, Muhammad, Gutierrez-Marcos, Jose, Gibson, Matthew I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394881/
https://www.ncbi.nlm.nih.gov/pubmed/30931129
http://dx.doi.org/10.1039/c8mh00727f