Allosteric inhibition of α-thrombin enzymatic activity with ultrasmall gold nanoparticles

The catalytic activity of enzymes can be regulated by interactions with synthetic nanoparticles (NPs) in a number of ways. To date, however, the potential use of NPs as allosteric effectors has not been investigated in detail. Importantly, targeting allosteric (distal) sites on the enzyme surface co...

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Detalles Bibliográficos
Autores principales: Lira, André L., Ferreira, Rodrigo S., Torquato, Ricardo J. S., Oliva, Maria Luiza V., Schuck, Peter, Sousa, Alioscka A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394888/
https://www.ncbi.nlm.nih.gov/pubmed/30931428
http://dx.doi.org/10.1039/c8na00081f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394888/
https://www.ncbi.nlm.nih.gov/pubmed/30931428
http://dx.doi.org/10.1039/c8na00081f

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