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Allosteric inhibition of α-thrombin enzymatic activity with ultrasmall gold nanoparticles
The catalytic activity of enzymes can be regulated by interactions with synthetic nanoparticles (NPs) in a number of ways. To date, however, the potential use of NPs as allosteric effectors has not been investigated in detail. Importantly, targeting allosteric (distal) sites on the enzyme surface co...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
RSC
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394888/ https://www.ncbi.nlm.nih.gov/pubmed/30931428 http://dx.doi.org/10.1039/c8na00081f |