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Complete protection of the BALB/c and C57BL/6J mice against Ebola and Marburg virus lethal challenges by pan-filovirus T-cell epigraph vaccine

There are a number of vaccine candidates under development against a small number of the most common outbreak filoviruses all employing the virus glycoprotein (GP) as the vaccine immunogen. However, antibodies induced by such GP vaccines are typically autologous and limited to the other members of t...

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Detalles Bibliográficos
Autores principales: Rahim, Md Niaz, Wee, Edmund G., He, Shihua, Audet, Jonathan, Tierney, Kevin, Moyo, Nathifa, Hannoun, Zara, Crook, Alison, Baines, Andrea, Korber, Bette, Qiu, Xiangguo, Hanke, Tomáš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394903/
https://www.ncbi.nlm.nih.gov/pubmed/30817809
http://dx.doi.org/10.1371/journal.ppat.1007564