A single nucleotide polymorphism in dopamine beta hydroxylase (rs6271(C>T)) is over-represented in inflammatory bowel disease patients and reduces circulating enzyme

Inflammatory bowel diseases (IBD) are associated with altered neuronal regulation of the gastrointestinal (GI) tract and release of norepinephrine (NE). As sympathetic innervation of the GI tract modulates motility, blood flow, and immune function, changes in NE signaling may alter the risk of devel...

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Detalles Bibliográficos
Autores principales: Gonzalez-Lopez, Eugene, Kawasawa-Imamura, Yuka, Zhang, Lijun, Huang, Xuemei, Koltun, Walter A., Coates, Matthew D., Vrana, Kent E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394932/
https://www.ncbi.nlm.nih.gov/pubmed/30817802
http://dx.doi.org/10.1371/journal.pone.0210175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394932/
https://www.ncbi.nlm.nih.gov/pubmed/30817802
http://dx.doi.org/10.1371/journal.pone.0210175

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