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Human cerebrospinal fluid 6E10-immunoreactive protein species contain amyloid precursor protein fragments

In a previous study, we reported that levels of two types of protein species—a type of ~55-kDa species and a type of ~15-kDa species—are elevated in the lumbar cerebrospinal fluid (CSF) of cognitively intact elderly individuals who are at risk for Alzheimer’s disease (AD). These species are immunore...

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Detalles Bibliográficos
Autores principales: Grant, Marianne K. O., Handoko, Maureen, Rozga, Malgorzata, Brinkmalm, Gunnar, Portelius, Erik, Blennow, Kaj, Ashe, Karen H., Zahs, Kathleen R., Liu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394962/
https://www.ncbi.nlm.nih.gov/pubmed/30817799
http://dx.doi.org/10.1371/journal.pone.0212815