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Anti-inflammatory microRNA-146a protects mice from diet-induced metabolic disease

Identifying regulatory mechanisms that influence inflammation in metabolic tissues is critical for developing novel metabolic disease treatments. Here, we investigated the role of microRNA-146a (miR-146a) during diet-induced obesity in mice. miR-146a is reduced in obese and type 2 diabetic patients...

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Detalles Bibliográficos
Autores principales: Runtsch, Marah C., Nelson, Morgan C., Lee, Soh-Hyun, Voth, Warren, Alexander, Margaret, Hu, Ruozhen, Wallace, Jared, Petersen, Charisse, Panic, Vanja, Villanueva, Claudio J., Evason, Kimberley J., Bauer, Kaylyn M., Mosbruger, Timothy, Boudina, Sihem, Bronner, Mary, Round, June L., Drummond, Micah J., O’Connell, Ryan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395003/
https://www.ncbi.nlm.nih.gov/pubmed/30768595
http://dx.doi.org/10.1371/journal.pgen.1007970