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Cyclical adaptation of measles virus quasispecies to epithelial and lymphocytic cells: To V, or not to V

Measles virus (MeV) is dual-tropic: it replicates first in lymphatic tissues and then in epithelial cells. This switch in tropism raises the question of whether, and how, intra-host evolution occurs. Towards addressing this question, we adapted MeV either to lymphocytic (Granta-519) or epithelial (H...

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Detalles Bibliográficos
Autores principales: Donohue, Ryan C., Pfaller, Christian K., Cattaneo, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395005/
https://www.ncbi.nlm.nih.gov/pubmed/30768648
http://dx.doi.org/10.1371/journal.ppat.1007605