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A poxvirus pseudokinase represses viral DNA replication via a pathway antagonized by its paralog kinase

Poxviruses employ sophisticated, but incompletely understood, signaling pathways that engage cellular defense mechanisms and simultaneously ensure viral factors are modulated properly. For example, the vaccinia B1 protein kinase plays a vital role in inactivating the cellular antiviral factor BAF, a...

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Detalles Bibliográficos
Autores principales: Olson, Annabel T., Wang, Zhigang, Rico, Amber B., Wiebe, Matthew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395007/
https://www.ncbi.nlm.nih.gov/pubmed/30768651
http://dx.doi.org/10.1371/journal.ppat.1007608