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A poxvirus pseudokinase represses viral DNA replication via a pathway antagonized by its paralog kinase
Poxviruses employ sophisticated, but incompletely understood, signaling pathways that engage cellular defense mechanisms and simultaneously ensure viral factors are modulated properly. For example, the vaccinia B1 protein kinase plays a vital role in inactivating the cellular antiviral factor BAF, a...
Autores principales: | Olson, Annabel T., Wang, Zhigang, Rico, Amber B., Wiebe, Matthew S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395007/ https://www.ncbi.nlm.nih.gov/pubmed/30768651 http://dx.doi.org/10.1371/journal.ppat.1007608 |
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