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Influence of Crohn’s disease related polymorphisms in innate immune function on ileal microbiome

We have previously identified NOD2 genotype and inflammatory bowel diseases (IBD) phenotype, as associated with shifts in the ileal microbiome (“dysbiosis”) in a patient cohort. Here we report an integrative analysis of an expanded number of Crohn's disease (CD) related genetic defects in innat...

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Detalles Bibliográficos
Autores principales: Li, Ellen, Zhang, Yuanhao, Tian, Xinyu, Wang, Xuefeng, Gathungu, Grace, Wolber, Ashley, Shiekh, Shehzad S., Sartor, R. Balfour, Davidson, Nicholas O., Ciorba, Matthew A., Zhu, Wei, Nelson, Leah M., Robertson, Charles E., Frank, Daniel N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395037/
https://www.ncbi.nlm.nih.gov/pubmed/30818349
http://dx.doi.org/10.1371/journal.pone.0213108