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Effect of deletion of the rgpA gene on selected virulence of Porphyromonas gingivalis

BACKGROUND/PURPOSE: The most potent virulence factors of the periodontal pathogen Porphyromonas gingivalis are gingipains, three cysteine proteases (RgpA, RgpB, and Kgp) that bind and cleave a wide range of host proteins. Considerable proof indicates that RgpA contributes to the entire virulence of...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Yang, Jie, Wu, Juan, Sun, Wei-Bin, Liu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association for Dental Sciences of the Republic of China 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395235/
https://www.ncbi.nlm.nih.gov/pubmed/30894985
http://dx.doi.org/10.1016/j.jds.2016.03.004