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Inhibition of PAK1 alleviates cerulein-induced acute pancreatitis via p38 and NF-κB pathways
Acute pancreatitis is a life-threatening disease accompanied by systemic inflammatory response. NF-κB and p38 signal pathways are activated in AP induced by cerulein. And PAKs are multifunctional effectors of Rho GTPases with kinase activity. In the present study, the function of P21-activated kinas...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Portland Press Ltd.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395303/ https://www.ncbi.nlm.nih.gov/pubmed/30718368 http://dx.doi.org/10.1042/BSR20182221 |