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Targeting the endoplasmic reticulum-mitochondria interface sensitizes leukemia cells to cytostatics

Combination chemotherapy has proven to be a favorable strategy to treat acute leukemia. However, the introduction of novel compounds remains challenging and is hindered by a lack of understanding of their mechanistic interactions with established drugs. In the present study, we demonstrate a highly...

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Detalles Bibliográficos
Autores principales: Koczian, Fabian, Nagło, Olga, Vomacka, Jan, Vick, Binje, Servatius, Phil, Zisis, Themistoklis, Hettich, Britta, Kazmaier, Uli, Sieber, Stephan A., Jeremias, Irmela, Zahler, Stefan, Braig, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395311/
https://www.ncbi.nlm.nih.gov/pubmed/30309851
http://dx.doi.org/10.3324/haematol.2018.197368