Transglutaminase 2 programs differentiating acute promyelocytic leukemia cells in all-trans retinoic acid treatment to inflammatory stage through NF-κB activation

Differentiation syndrome (DS) is a life-threatening complication arising during retinoid treatment of acute promyelocytic leukemia (APL). Administration of all-trans retinoic acid leads to significant changes in gene expression, among the most induced of which is transglutaminase 2, which is not nor...

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Detalles Bibliográficos
Autores principales: Jambrovics, Károly, Uray, Iván P., Keresztessy, Zsolt, Keillor, Jeffrey W., Fésüs, László, Balajthy, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395331/
https://www.ncbi.nlm.nih.gov/pubmed/30237268
http://dx.doi.org/10.3324/haematol.2018.192823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395331/
https://www.ncbi.nlm.nih.gov/pubmed/30237268
http://dx.doi.org/10.3324/haematol.2018.192823

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