Metformin Suppresses Hypopharyngeal Cancer Growth by Epigenetically Silencing Long Non-coding RNA SNHG7 in FaDu Cells

Local recurrence after therapy remains a challenging problem for hypopharyngeal cancer (HPC) due to the chemotherapy resistance. Metformin is associated with reduced cancer risk through promoting global DNA methylation in cancer cells by controlling S-adenosylhomocysteine (SAHH) activity. However, t...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Ping, Tang, Yaoyun, Fang, Xing, Xie, Chubo, Zeng, Junfeng, Wang, Wei, Zhao, Suping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395377/
https://www.ncbi.nlm.nih.gov/pubmed/30853913
http://dx.doi.org/10.3389/fphar.2019.00143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395377/
https://www.ncbi.nlm.nih.gov/pubmed/30853913
http://dx.doi.org/10.3389/fphar.2019.00143

Ejemplares similares