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ProNGF and Neurodegeneration in Alzheimer’s Disease

Profound and early basal forebrain cholinergic neuron (BFCN) degeneration is a hallmark of Alzheimer’s disease (AD). Loss of synapses between basal forebrain and hippocampal and cortical target tissue correlates highly with the degree of dementia and is thought to be a major contributor to memory lo...

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Detalles Bibliográficos
Autores principales: Fahnestock, Margaret, Shekari, Arman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395390/
https://www.ncbi.nlm.nih.gov/pubmed/30853882
http://dx.doi.org/10.3389/fnins.2019.00129