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Cognate Interaction With CD4(+) T Cells Instructs Tumor-Associated Macrophages to Acquire M1-Like Phenotype

The immunosuppressive tumor microenvironment (TME) established by tumor cells, stromal cells and inhibitory immune cells counteracts the function of tumor reactive T cells. Tumor associated macrophages (TAMs) showing functional plasticity contribute to this process as so called M2-like macrophages c...

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Detalles Bibliográficos
Autores principales: Eisel, David, Das, Krishna, Dickes, Elke, König, Rainer, Osen, Wolfram, Eichmüller, Stefan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395406/
https://www.ncbi.nlm.nih.gov/pubmed/30853959
http://dx.doi.org/10.3389/fimmu.2019.00219