Mitochondrial Dysfunction in Astrocytes Impairs the Generation of Reactive Astrocytes and Enhances Neuronal Cell Death in the Cortex Upon Photothrombotic Lesion

Mitochondria are key organelles in regulating the metabolic state of a cell. In the brain, mitochondrial oxidative metabolism is the prevailing mechanism for neurons to generate ATP. While it is firmly established that neuronal function is highly dependent on mitochondrial metabolism, it is less wel...

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Detalles Bibliográficos
Autores principales: Fiebig, Christian, Keiner, Silke, Ebert, Birgit, Schäffner, Iris, Jagasia, Ravi, Lie, D. Chichung, Beckervordersandforth, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395449/
https://www.ncbi.nlm.nih.gov/pubmed/30853890
http://dx.doi.org/10.3389/fnmol.2019.00040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395449/
https://www.ncbi.nlm.nih.gov/pubmed/30853890
http://dx.doi.org/10.3389/fnmol.2019.00040

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