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Mitochondrial Dysfunction in Astrocytes Impairs the Generation of Reactive Astrocytes and Enhances Neuronal Cell Death in the Cortex Upon Photothrombotic Lesion
Mitochondria are key organelles in regulating the metabolic state of a cell. In the brain, mitochondrial oxidative metabolism is the prevailing mechanism for neurons to generate ATP. While it is firmly established that neuronal function is highly dependent on mitochondrial metabolism, it is less wel...
Autores principales: | Fiebig, Christian, Keiner, Silke, Ebert, Birgit, Schäffner, Iris, Jagasia, Ravi, Lie, D. Chichung, Beckervordersandforth, Ruth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395449/ https://www.ncbi.nlm.nih.gov/pubmed/30853890 http://dx.doi.org/10.3389/fnmol.2019.00040 |
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