Suppression of Akt-mTOR pathway rescued the social behavior in Cntnap2-deficient mice

Autism spectrum disorders (ASD) form a heterogeneous, neurodevelopmental syndrome characterized by deficits in social interactions and repetitive behavior/restricted interests. Dysregulation of mTOR signaling has been implicated in the pathogenesis of certain types of ASD, and inhibition of mTOR by...

Descripción completa

Detalles Bibliográficos
Autores principales: Xing, Xiaoliang, Zhang, Jing, Wu, Kunyang, Cao, Beibei, Li, Xianfeng, Jiang, Fang, Hu, Zhengmao, Xia, Kun, Li, Jia-Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395585/
https://www.ncbi.nlm.nih.gov/pubmed/30816216
http://dx.doi.org/10.1038/s41598-019-39434-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395585/
https://www.ncbi.nlm.nih.gov/pubmed/30816216
http://dx.doi.org/10.1038/s41598-019-39434-5

Ejemplares similares