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Suppression of Akt-mTOR pathway rescued the social behavior in Cntnap2-deficient mice

Autism spectrum disorders (ASD) form a heterogeneous, neurodevelopmental syndrome characterized by deficits in social interactions and repetitive behavior/restricted interests. Dysregulation of mTOR signaling has been implicated in the pathogenesis of certain types of ASD, and inhibition of mTOR by...

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Detalles Bibliográficos
Autores principales:	Xing, Xiaoliang, Zhang, Jing, Wu, Kunyang, Cao, Beibei, Li, Xianfeng, Jiang, Fang, Hu, Zhengmao, Xia, Kun, Li, Jia-Da
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395585/ https://www.ncbi.nlm.nih.gov/pubmed/30816216 http://dx.doi.org/10.1038/s41598-019-39434-5

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