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A novel liver-specific fluorescent anti-cancer drug delivery system using indocyanine green

Indocyanine green (ICG) accumulates only in hepatocytes and their malignant counterpart, hepatocellular carcinoma (HCC). We have developed ICG-conjugated anti-cancer drugs and noted their significant accumulation in HCC cells both in vitro and in vivo. ICG-conjugated gemcitabine was less toxic to no...

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Detalles Bibliográficos
Autores principales: Inagaki, Yoshinori, Kokudo, Takashi, Kamiya, Mako, Uno, Shin-nosuke, Sato, Masumitsu, Kaneko, Junichi, Kokudo, Norihiro, Urano, Yasuteru, Hasegawa, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395603/
https://www.ncbi.nlm.nih.gov/pubmed/30816163
http://dx.doi.org/10.1038/s41598-019-39269-0