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Comparison of null models for combination drug therapy reveals Hand model as biochemically most plausible
Null models for the effect of combination therapies are widely used to evaluate synergy and antagonism of drugs. Due to the relevance of null models, their suitability is continuously discussed. Here, we contribute to the discussion by investigating the properties of five null models. Our study incl...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395630/ https://www.ncbi.nlm.nih.gov/pubmed/30816136 http://dx.doi.org/10.1038/s41598-019-38907-x |