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Cancer associated fibroblasts sculpt tumour microenvironment by recruiting monocytes and inducing immunosuppressive PD-1(+) TAMs

Fibroblasts turn into cancer associated fibroblasts (CAFs) in the tumour microenvironment. CAFs have recently attracted attention for their function as a regulator of immune cell recruitment and function in addition to their tumour-promoting roles. In this study, we aimed to determine the role of CA...

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Detalles Bibliográficos
Autores principales: Gok Yavuz, Betul, Gunaydin, Gurcan, Gedik, M. Emre, Kosemehmetoglu, Kemal, Karakoc, Derya, Ozgur, Figen, Guc, Dicle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395633/
https://www.ncbi.nlm.nih.gov/pubmed/30816272
http://dx.doi.org/10.1038/s41598-019-39553-z