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Leveraging brain cortex-derived molecular data to elucidate epigenetic and transcriptomic drivers of complex traits and disease

Integrative approaches that harness large-scale molecular datasets can help develop mechanistic insight into findings from genome-wide association studies (GWAS). We have performed extensive analyses to uncover transcriptional and epigenetic processes which may play a role in complex trait variation...

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Detalles Bibliográficos
Autores principales: Hatcher, Charlie, Relton, Caroline L., Gaunt, Tom R., Richardson, Tom G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395652/
https://www.ncbi.nlm.nih.gov/pubmed/30820025
http://dx.doi.org/10.1038/s41398-019-0437-2