DGAT1 Inhibitor Suppresses Prostate Tumor Growth and Migration by Regulating Intracellular Lipids and Non-Centrosomal MTOC Protein GM130

Acyl-CoA:diacylglycerol acyltransferase I (DGAT1) is a key enzyme in lipogenesis which is increased in metabolically active cells to meet nutrient requirements. DGAT1 has been recognized as an anti-obesity target; however, its role in the tumor microenvironment remains unclear. We postulated that, i...

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Detalles Bibliográficos
Autores principales: Nardi, Francesca, Franco, Omar E., Fitchev, Philip, Morales, Alejandro, Vickman, Renee E., Hayward, Simon W., Crawford, Susan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395665/
https://www.ncbi.nlm.nih.gov/pubmed/30816200
http://dx.doi.org/10.1038/s41598-019-39537-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395665/
https://www.ncbi.nlm.nih.gov/pubmed/30816200
http://dx.doi.org/10.1038/s41598-019-39537-z

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