Efficient cell penetration and delivery of peptide nucleic acids by an argininocalix[4]arene

The application of Peptide Nucleic Acids (PNAs), mimics of DNA lacking the sugar-phosphate backbone, for antisense/anti-gene therapy and gene editing is limited by their low uptake by cells. Currently, no simple and efficient delivery systems and methods are available to solve this open issue. One o...

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Detalles Bibliográficos
Autores principales: Gasparello, Jessica, Manicardi, Alex, Casnati, Alessandro, Corradini, Roberto, Gambari, Roberto, Finotti, Alessia, Sansone, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395679/
https://www.ncbi.nlm.nih.gov/pubmed/30816154
http://dx.doi.org/10.1038/s41598-019-39211-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395679/
https://www.ncbi.nlm.nih.gov/pubmed/30816154
http://dx.doi.org/10.1038/s41598-019-39211-4

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