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deMix: Decoding Deuterated Distributions from Heterogeneous Protein States via HDX-MS
Characterization of protein structural changes in response to protein modifications, ligand or chemical binding, or protein-protein interactions is essential for understanding protein function and its regulation. Amide hydrogen/deuterium exchange (HDX) coupled with mass spectrometry (MS) is one of t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395696/ https://www.ncbi.nlm.nih.gov/pubmed/30816214 http://dx.doi.org/10.1038/s41598-019-39512-8 |