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deMix: Decoding Deuterated Distributions from Heterogeneous Protein States via HDX-MS

Characterization of protein structural changes in response to protein modifications, ligand or chemical binding, or protein-protein interactions is essential for understanding protein function and its regulation. Amide hydrogen/deuterium exchange (HDX) coupled with mass spectrometry (MS) is one of t...

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Detalles Bibliográficos
Autores principales: Na, Seungjin, Lee, Jae-Jin, Joo, Jong Wha J., Lee, Kong-Joo, Paek, Eunok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395696/
https://www.ncbi.nlm.nih.gov/pubmed/30816214
http://dx.doi.org/10.1038/s41598-019-39512-8