Identification of an XRCC1 DNA binding activity essential for retention at sites of DNA damage

Repair of two major forms of DNA damage, single strand breaks and base modifications, are dependent on XRCC1. XRCC1 orchestrates these repair processes by temporally and spatially coordinating interactions between several other repair proteins. Here we show that XRCC1 contains a central DNA binding...

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Detalles Bibliográficos
Autores principales: Mok, Mac C. Y., Campalans, Anna, Pillon, Monica C., Guarné, Alba, Radicella, J. Pablo, Junop, Murray S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395731/
https://www.ncbi.nlm.nih.gov/pubmed/30816207
http://dx.doi.org/10.1038/s41598-019-39543-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395731/
https://www.ncbi.nlm.nih.gov/pubmed/30816207
http://dx.doi.org/10.1038/s41598-019-39543-1

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