Cargando…
Identification of an XRCC1 DNA binding activity essential for retention at sites of DNA damage
Repair of two major forms of DNA damage, single strand breaks and base modifications, are dependent on XRCC1. XRCC1 orchestrates these repair processes by temporally and spatially coordinating interactions between several other repair proteins. Here we show that XRCC1 contains a central DNA binding...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395731/ https://www.ncbi.nlm.nih.gov/pubmed/30816207 http://dx.doi.org/10.1038/s41598-019-39543-1 |