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Computational identification of co-evolving multi-gene modules in microbial biosynthetic gene clusters
The biosynthetic machinery responsible for the production of bacterial specialised metabolites is encoded by physically clustered group of genes called biosynthetic gene clusters (BGCs). The experimental characterisation of numerous BGCs has led to the elucidation of subclusters of genes within BGCs...
Autores principales: | Del Carratore, Francesco, Zych, Konrad, Cummings, Matthew, Takano, Eriko, Medema, Marnix H., Breitling, Rainer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395733/ https://www.ncbi.nlm.nih.gov/pubmed/30854475 http://dx.doi.org/10.1038/s42003-019-0333-6 |
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