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Treatment with maresin 1, a docosahexaenoic acid-derived pro-resolution lipid, protects skin from inflammation and oxidative stress caused by UVB irradiation

Acute exposure to UVB irradiation causes skin inflammation and oxidative stress, and long-term exposure to UVB irradiation may lead to carcinogenesis. Our organism has endogenous mechanisms to actively limit inflammation. Maresin 1 (MaR1; 7R,14S-dihydroxy-docosa-4Z,8E,10E,12Z,16Z,19Z-hexaenoic acid)...

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Detalles Bibliográficos
Autores principales: Cezar, Talita L. C., Martinez, Renata M., Rocha, Camila da, Melo, Cristina P. B., Vale, David L., Borghi, Sergio M., Fattori, Victor, Vignoli, Josiane A., Camilios-Neto, Doumit, Baracat, Marcela M., Georgetti, Sandra R., Verri, Waldiceu A., Casagrande, Rubia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395735/
https://www.ncbi.nlm.nih.gov/pubmed/30816324
http://dx.doi.org/10.1038/s41598-019-39584-6