Cargando…

Elucidating the Contribution of Skeletal Muscle Ion Channels to Amyotrophic Lateral Sclerosis in search of new therapeutic options

The discovery of pathogenetic mechanisms is essential to identify new therapeutic approaches in Amyotrophic Lateral Sclerosis (ALS). Here we investigated the role of the most important ion channels in skeletal muscle of an ALS animal model (MLC/SOD1(G93A)) carrying a mutated SOD1 exclusively in this...

Descripción completa

Detalles Bibliográficos
Autores principales: Camerino, Giulia Maria, Fonzino, Adriano, Conte, Elena, De Bellis, Michela, Mele, Antonietta, Liantonio, Antonella, Tricarico, Domenico, Tarantino, Nancy, Dobrowolny, Gabriella, Musarò, Antonio, Desaphy, Jean-Francois, De Luca, Annamaria, Pierno, Sabata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395744/
https://www.ncbi.nlm.nih.gov/pubmed/30816241
http://dx.doi.org/10.1038/s41598-019-39676-3