Brain-stiffness-mimicking tilapia collagen gel promotes the induction of dorsal cortical neurons from human pluripotent stem cells

The mechanical properties of the extracellular microenvironment, including its stiffness, play a crucial role in stem cell fate determination. Although previous studies have demonstrated that the developing brain exhibits spatiotemporal diversity in stiffness, it remains unclear how stiffness regula...

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Detalles Bibliográficos
Autores principales: Iwashita, Misato, Ohta, Hatsumi, Fujisawa, Takahiro, Cho, Minyoung, Ikeya, Makoto, Kidoaki, Satoru, Kosodo, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395773/
https://www.ncbi.nlm.nih.gov/pubmed/30816128
http://dx.doi.org/10.1038/s41598-018-38395-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395773/
https://www.ncbi.nlm.nih.gov/pubmed/30816128
http://dx.doi.org/10.1038/s41598-018-38395-5

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