Alternative splicing of the Izumo1 gene ensures triggering gamete fusion in mice

IZUMO1 is a sperm acrosomal membrane protein that is essential for mammalian fertilization through recognition of JUNO on the oocyte surface and accompanying IZUMO1-JUNO complex formation. Here, we report a new Izumo1 gene splicing variant (IZUMO1_v2) with a unique 52-amino-acid-long signal sequence...

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Detalles Bibliográficos
Autores principales: Saito, Takako, Wada, Ikuo, Inoue, Naokazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395798/
https://www.ncbi.nlm.nih.gov/pubmed/30816314
http://dx.doi.org/10.1038/s41598-019-40130-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395798/
https://www.ncbi.nlm.nih.gov/pubmed/30816314
http://dx.doi.org/10.1038/s41598-019-40130-7

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