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Assessing the effects of Ang-(1-7) therapy following transient middle cerebral artery occlusion

The counter-regulatory axis, Angiotensin Converting Enzyme 2, Angiotensin-(1-7), Mas receptor (ACE2/Ang-1-7/MasR), of the renin angiotensin system (RAS) is a potential therapeutic target in stroke, with Ang-(1-7) reported to have neuroprotective effects in pre-clinical stroke models. Here, an extens...

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Detalles Bibliográficos
Autores principales: Arroja, M. M. C., Reid, E., Roy, L. A., Vallatos, A. V., Holmes, W. M., Nicklin, S. A., Work, L. M., McCabe, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395816/
https://www.ncbi.nlm.nih.gov/pubmed/30816157
http://dx.doi.org/10.1038/s41598-019-39102-8