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Hidden in plain sight: what remains to be discovered in the eukaryotic proteome?

The first decade of genome sequencing stimulated an explosion in the characterization of unknown proteins. More recently, the pace of functional discovery has slowed, leaving around 20% of the proteins even in well-studied model organisms without informative descriptions of their biological roles. R...

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Detalles Bibliográficos
Autores principales: Wood, Valerie, Lock, Antonia, Harris, Midori A., Rutherford, Kim, Bähler, Jürg, Oliver, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395881/
https://www.ncbi.nlm.nih.gov/pubmed/30938578
http://dx.doi.org/10.1098/rsob.180241