Cargando…
Nox1/Ref-1-mediated activation of CREB promotes Gremlin1-driven endothelial cell proliferation and migration
Pulmonary arterial hypertension (PAH) is a complex degenerative disorder marked by aberrant vascular remodeling associated with hyperproliferation and migration of endothelial cells (ECs). Previous reports implicated bone morphogenetic protein antagonist Gremlin 1 in this process; however, little is...
Autores principales: | de Jesus, Daniel S., DeVallance, Evan, Li, Yao, Falabella, Micol, Guimaraes, Danielle, Shiva, Sruti, Kaufman, Brett A., Gladwin, Mark T., Pagano, Patrick J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395885/ https://www.ncbi.nlm.nih.gov/pubmed/30802716 http://dx.doi.org/10.1016/j.redox.2019.101138 |
Ejemplares similares
-
Niche formed by bone morphogenetic protein antagonists gremlin 1 and gremlin 2 in human hair follicles
por: Niiyama, Shiro, et al.
Publicado: (2022) -
Specificity Protein 1-Mediated Promotion of CXCL12 Advances Endothelial Cell Metabolism and Proliferation in Pulmonary Hypertension
por: DeVallance, Evan R., et al.
Publicado: (2022) -
Gremlin-1 Concentrations Are Correlated with the Severity of Knee Osteoarthritis
por: Yi, Jun, et al.
Publicado: (2016) -
Production and Biochemical Characterization of Dimeric Recombinant Gremlin-1
por: Mitola, Stefania, et al.
Publicado: (2022) -
Circulating Gremlin-1 is elevated in systemic sclerosis
patients
por: O’Reilly, Steven
Publicado: (2021)