Cargando…
Efficient Pre-mRNA Cleavage Prevents Replication-Stress-Associated Genome Instability
Cellular mechanisms that safeguard genome integrity are often subverted in cancer. To identify cancer-related genome caretakers, we employed a convergent multi-screening strategy coupled to quantitative image-based cytometry and ranked candidate genes according to multivariate readouts reflecting vi...
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395949/ https://www.ncbi.nlm.nih.gov/pubmed/30639241 http://dx.doi.org/10.1016/j.molcel.2018.11.036 |