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Microvesicles containing miR-34a induce apoptosis of proximal tubular epithelial cells and participate in renal interstitial fibrosis

Function and potential mechanism of microvesicles (MVs) containing microRNA34a in renal interstitial fibrosis were investigated. A rat model of renal interstitial fibrosis was established by unilateral ureteral ligation (UUO). Rat proximal tubular epithelial cell line (NRK-52E) was used to explore t...

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Detalles Bibliográficos
Autores principales: Li, Hongyan, Xu, Yuexia, Zhang, Qin, Xu, Hongfang, Xu, Yan, Ling, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396007/
https://www.ncbi.nlm.nih.gov/pubmed/30867715
http://dx.doi.org/10.3892/etm.2019.7197