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Stapled Peptides Inhibitors: A New Window for Target Drug Discovery

Protein-protein interaction (PPI) is a hot topic in clinical research as protein networking has a major impact in human disease. Such PPIs are potential drugs targets, leading to the need to inhibit/block specific PPIs. While small molecule inhibitors have had some success and reached clinical trial...

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Detalles Bibliográficos
Autores principales: Ali, Ameena M., Atmaj, Jack, Van Oosterwijk, Niels, Groves, Matthew R., Dömling, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396041/
https://www.ncbi.nlm.nih.gov/pubmed/30867891
http://dx.doi.org/10.1016/j.csbj.2019.01.012