The selective mineralocorticoid receptor modulator AZD9977 reveals differences in mineralocorticoid effects of aldosterone and fludrocortisone

INTRODUCTION: AZD9977 is a novel mineralocorticoid receptor (MR) modulator, which in preclinical studies demonstrated organ protection without affecting aldosterone-regulated urinary electrolyte excretion. However, when tested in humans, using fludrocortisone as an MR agonist, AZD9977 exhibited simi...

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Detalles Bibliográficos
Autores principales: Bamberg, Krister, William-Olsson, Lena, Johansson, Ulrika, Jansson-Löfmark, Rasmus, Hartleib-Geschwindner, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396052/
https://www.ncbi.nlm.nih.gov/pubmed/30813831
http://dx.doi.org/10.1177/1470320319827449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396052/
https://www.ncbi.nlm.nih.gov/pubmed/30813831
http://dx.doi.org/10.1177/1470320319827449

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