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The selective mineralocorticoid receptor modulator AZD9977 reveals differences in mineralocorticoid effects of aldosterone and fludrocortisone

INTRODUCTION: AZD9977 is a novel mineralocorticoid receptor (MR) modulator, which in preclinical studies demonstrated organ protection without affecting aldosterone-regulated urinary electrolyte excretion. However, when tested in humans, using fludrocortisone as an MR agonist, AZD9977 exhibited simi...

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Detalles Bibliográficos
Autores principales:	Bamberg, Krister, William-Olsson, Lena, Johansson, Ulrika, Jansson-Löfmark, Rasmus, Hartleib-Geschwindner, Judith
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2019
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396052/ https://www.ncbi.nlm.nih.gov/pubmed/30813831 http://dx.doi.org/10.1177/1470320319827449

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