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Microheterogeneity of Topoisomerase IA/IB and Their DNA-Bound States

[Image: see text] Topoisomerases are important complex enzymes that modulate DNA topology to maintain chromosome superstructure and integrity. These enzymes are involved in many cellular processes that resolve specific DNA superstructures and intermediates. The low abundance combined with the biolog...

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Detalles Bibliográficos
Autores principales: Jeanne Dit Fouque, Kevin, Garabedian, Alyssa, Leng, Fenfei, Tse-Dinh, Yuk-Ching, Fernandez-Lima, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396120/
https://www.ncbi.nlm.nih.gov/pubmed/30842985
http://dx.doi.org/10.1021/acsomega.8b02887