Solution Structure of a MYC Promoter G-Quadruplex with 1:6:1 Loop Length

[Image: see text] The important MYC oncogene is deregulated in many cancer cells and comprises one of the most prominent G-quadruplex (G4) forming sequences in its promoter regions, the NHE III(1) motif. Formation of G4s suppresses MYC transcription and can be modulated by drug binding, establishing...

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Detalles Bibliográficos
Autores principales: Dickerhoff, Jonathan, Onel, Buket, Chen, Luying, Chen, Yuwei, Yang, Danzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396123/
https://www.ncbi.nlm.nih.gov/pubmed/30842981
http://dx.doi.org/10.1021/acsomega.8b03580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396123/
https://www.ncbi.nlm.nih.gov/pubmed/30842981
http://dx.doi.org/10.1021/acsomega.8b03580

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