Efficacy of celastrol combined with cisplatin in enhancing the apoptosis of U-2OS osteosarcoma cells via the mitochondrial and endoplasmic reticulum pathways of apoptosis

Osteosarcoma is a common primary malignant tumor of bone, and the poor prognosis and low 5-year survival rate have not improved for three decades. The present study aimed to study the effect a combination of celastrol and cisplatin on the human osteosarcoma cell line U-2OS, and to investigate the me...

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Detalles Bibliográficos
Autores principales: Wang, Qiang, Yu, Xiaolong, Li, Fan, Lv, Xin, Fu, Xiaoxing, Gu, Houyun, Liu, Hucheng, Liu, Jun, Dai, Min, Zhang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396172/
https://www.ncbi.nlm.nih.gov/pubmed/30867764
http://dx.doi.org/10.3892/ol.2019.10007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396172/
https://www.ncbi.nlm.nih.gov/pubmed/30867764
http://dx.doi.org/10.3892/ol.2019.10007

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