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Computational Evolution of Threonine-Rich β-Hairpin Peptides Mimicking Specificity and Affinity of Antibodies

[Image: see text] The development of recognition molecules with antibody-like properties is of great value to the biotechnological and bioanalytical communities. The recognition molecules presented here are peptides with a strong tendency to form β-hairpin structures, stabilized by alternate threoni...

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Detalles Bibliográficos
Autores principales: Hu, Hongxia, Kofoed, Christian, Li, Ming, Gonçalves, Juliana Pereira Lopes, Hansen, Jonas, Wolfram, Martin, Hansen, Axel Kornerup, Friis Hansen, Camilla Hartmann, Diness, Frederik, Schoffelen, Sanne, Meldal, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396188/
https://www.ncbi.nlm.nih.gov/pubmed/30834314
http://dx.doi.org/10.1021/acscentsci.8b00614