Sustained Melanopsin Photoresponse Is Supported by Specific Roles of β-Arrestin 1 and 2 in Deactivation and Regeneration of Photopigment

Melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs) are indispensable for non-image-forming visual responses that sustain under prolonged illumination. For sustained signaling of ipRGCs, the melanopsin photopigment must continuously regenerate. The underlying mechanism...

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Detalles Bibliográficos
Autores principales: Mure, Ludovic S., Hatori, Megumi, Ruda, Kiersten, Benegiamo, Giorgia, Demas, James, Panda, Satchidananda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396282/
https://www.ncbi.nlm.nih.gov/pubmed/30485815
http://dx.doi.org/10.1016/j.celrep.2018.11.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396282/
https://www.ncbi.nlm.nih.gov/pubmed/30485815
http://dx.doi.org/10.1016/j.celrep.2018.11.008

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