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Predicting time to dementia using a quantitative template of disease progression
INTRODUCTION: Characterization of longitudinal trajectories of biomarkers implicated in sporadic Alzheimer's disease (AD) in decades before clinical diagnosis is important for disease prevention and monitoring. METHODS: We used a multivariate Bayesian model to temporally align 1369 Alzheimer...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396328/ https://www.ncbi.nlm.nih.gov/pubmed/30859120 http://dx.doi.org/10.1016/j.dadm.2019.01.005 |